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NEJM published first CTX001 CRISPR patient cases for sickle cell and β-thalassemia

Dated 5 December 2020: NEJM published first CTX001 CRISPR patient cases for sickle cell and β-thalassemia. In the causal graph this event strengthens the driver Gene-Editing Diffusion.

Who was responsible

Contribution type and responsibility level for each recorded actor — not sole-author shorthand.

No public contributors are listed for this fact.

What changed

Fact → Driver → Indicator. Relationship strength orders the paths; it is not the observed indicator movement.

    1. FactNEJM published first CTX001 CRISPR patient cases for sickle cell and β-thalassemia
    2. strengthensDriverGene-Editing Diffusion

    provisional weight · verified

Causal path

How this event connects to drivers and indicators in the graph.

  1. FactNEJM published first CTX001 CRISPR patient cases for sickle cell and β-thalassemia
  2. strengthensDriverGene-Editing Diffusion

Cite this page

Factrail. (2026). NEJM published first CTX001 CRISPR patient cases for sickle cell and β-thalassemia. Factrail. https://factrail.ai/facts/frangoul-nejm-ctx001-sickle-thalassemia-december-2020

https://factrail.ai/facts/frangoul-nejm-ctx001-sickle-thalassemia-december-2020

Accessed 16 October 2026.

By the Factrail desk · Method: how we source and score · Last reviewed

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